Myokines in Appetite Control and Energy Balance

Efficacy of obesity treatments varies between individuals, highlighting the presence responders and non-responders. Whilst exercise alone or combined with diet leads to underwhelming weight loss for most, there exist super losing significant weight. Furthermore, in response loss, majority but not all patients tend regain Within biopsychosocial model, biology as a determinant has been underappreciated. The understanding role that organs beyond adipose tissue gastrointestinal tract play appetite control body regulation developed recent years. aim this review is highlight potential myokines may be important physiology overall energy balance. A number attractive targets are described warrant further investigation. deeper how these drive feeding behaviours improve measures prevent treat through precision medicine approach.